John Snow's Cholera Map, 1854
In the summer of 1854, a cholera outbreak tore through the Soho district of London. Within days, the outbreak — centred on Broad Street and Golden Square — had killed 616 people. The physician John Snow, already sceptical of the prevailing theory that disease travelled through bad air, set about tracing the deaths street by street. Using bars to mark each death's location on a map of the neighbourhood, he was able to show that the cases clustered around a single public water pump on Broad Street — and that contaminated water, not miasma, was the cause.
Snow's study became a founding moment of modern epidemiology, and its consequences were immediate: it changed the design of London's water and waste systems, and set a new standard for public health investigation worldwide. The map he commissioned — published in the second edition of his essay On the Mode of Communication of Cholera in 1855 — has become one of the most reproduced documents in the history of science. It is both a piece of rigorous data analysis and something quietly beautiful: a portrait of a neighbourhood rendered as evidence.